INAP
Publications
The intra-oral negative air pressure (iNAP) therapy has earned 155 patents issued worldwide and has been featured in more than 35 publications in peer-reviewed journals.
According to iNAP® One Pivotal Study, 88% of patients reported a significant improvement and the therapy demonstrated a 75% clinical success rate.
This study has been accepted for publication in the Journal of Sleep Medicine.
Publication List
Journal Paper :
1. C.Y. Cheng et al. – “Evaluation of efficacy and safety of intraoral negative air pressure device in adults with obstructive sleep apnea in Taiwan”, Sleep Medicine, vol. 81 (2021). Link
2. Y.-H. Kuo, T.-J. Liu, et al. – “Novel Intraoral Negative Airway Pressure in Drug-Induced Sleep Endoscopy with Target-Controlled Infusion”, Nat Sci Sleep. 2021. Link
3. T. C. Hung et al. – “Building a model to precisely target the responders of a novel intermittent negative air pressure device-with mechanism definition”, Sleep Medicine, vol. 72 (2020). Link
Abstract:
Novel Intraoral Negative Airway Pressure in Drug-Induced Sleep Endoscopy with Target-Controlled Infusion
Author information:
Yu-Hsuan Kuo, Tien-Jen Liu, Feng-Hsiang Chiu, Yi Chang, Chia-Mo Lin, Ofer Jacobowitz, และ Ying-Shuo Hsu
4. Y. Yamaguchi – “The Effect of Intermittent Negative Air Pressure, iNAP® on Subjective Daytime Sleepiness in Middle-aged Patients with Moderate Obstructive Sleep Apnea”, J. Sleep Disord. Ther., vol.9, Iss.5, 2020. Link
5. T. C. Hung et al. – “A novel intermittent negative air pressure device ameliorates obstructive sleep apnea syndrome in adults”, Sleep Breath., vol. 23, no. 3, 2019. Link
7. M. Camacho, S. A. Song, and A. M. Tolisano – “Oral pressure therapy (winx) for obstructive sleep apnea: a meta-analysis updating the systematic review”, Sleep Breath., vol. 20, no. 3, 2016. Link
8. G. Nigam, C. Pathak, and M. Riaz – “Effectiveness of oral pressure therapy in obstructive sleep apnea: a systematic analysis”, Sleep Breath., vol. 20, no. 2, 2016. Link
9. R. J. Schwab et al. – “Examining the Mechanism of Action of a New Device Using Oral Pressure Therapy for the Treatment of Obstructive Sleep Apnea”, Sleep, vol. 37, no. 7, 2014. Link
10. I. M. Colrain et al. – “A multicenter evaluation of oral pressure therapy for the treatment of obstructive sleep apnea”, Sleep Med., vol. 14, no. 9, 2013. Link
11. J. G. Park, T. M. Morgenthaler, and P. C. Gay – “Novel and emerging nonpositive airway pressure therapies for sleep apnea”, Chest, vol. 144, no. 6, 2013. Link
12. D. A. Barone – “Alternative devices for obstructive sleep apnea”, Neurol. Clin. Pract., vol. 3, no. 1, 2013. Link
13. Y.-T. Tseng, C.-J. Kuo, C.-Y. Lai – “Evaluating the mechanisms of the innovative negative pressure therapy for obstructive sleep apnea treatment by upper airway dynamic imaging”, Fu-Jen Journal of Medicine 19(4):30-38, 2021.
Conference Papers
- Georg N et al. – “A Multi-center, Two-stage, Single-arm, Prospective, First-night Order Cross-over, Evaluator-blind Study to Evaluate the Efficacy, Safety and Tolerance of the iNAP® Sleep Therapy System in Adults with Obstructive Sleep Apnea (OSA)–AN INTERIM ANALYSIS”, 27th DGSM, 2019, Germany.
- Liu CL et al. – “Intra-oral negative pressure therapy in patients with obstructive sleep apnea: upper airway imaging in responders vs. nonresponses”, Sleep Down Under, 2019, Australia. … and many more.
